Severity: 8192
Message: Creation of dynamic property CI_URI::$config is deprecated
Filename: core/URI.php
Line Number: 101
Backtrace:
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property CI_Router::$uri is deprecated
Filename: core/Router.php
Line Number: 127
Backtrace:
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$benchmark is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$hooks is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$config is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$log is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$utf8 is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$uri is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$exceptions is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$router is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$output is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$security is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$input is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$lang is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$db is deprecated
Filename: core/Loader.php
Line Number: 396
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property CI_DB_mysqli_driver::$failover is deprecated
Filename: database/DB_driver.php
Line Number: 371
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::open($save_path, $name) should either be compatible with SessionHandlerInterface::open(string $path, string $name): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 132
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::close() should either be compatible with SessionHandlerInterface::close(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 294
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::read($session_id) should either be compatible with SessionHandlerInterface::read(string $id): string|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 168
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::write($session_id, $session_data) should either be compatible with SessionHandlerInterface::write(string $id, string $data): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 237
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::destroy($session_id) should either be compatible with SessionHandlerInterface::destroy(string $id): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 317
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::gc($maxlifetime) should either be compatible with SessionHandlerInterface::gc(int $max_lifetime): int|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 282
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: session_set_cookie_params(): Session cookie parameters cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 289
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 304
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 314
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 315
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 316
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 317
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 375
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: session_set_save_handler(): Session save handler cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 110
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: Warning
Message: session_start(): Session cannot be started after headers have already been sent
Filename: Session/Session.php
Line Number: 143
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$session is deprecated
Filename: core/Loader.php
Line Number: 1283
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$pagination is deprecated
Filename: core/Loader.php
Line Number: 1283
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 17
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property Website_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
Line: 15
Function: _error_handler
File: /home/websi113/case/germark.com.tw/application/models/Website_model.php
Line: 7
Function: __construct
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 52
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$Website_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 52
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: News_model::getList(): Optional parameter $search declared before required parameter $perPage is implicitly treated as a required parameter
Filename: models/News_model.php
Line Number: 10
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 53
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
Line: 15
Function: _error_handler
File: /home/websi113/case/germark.com.tw/application/models/News_model.php
Line: 7
Function: __construct
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 53
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$News_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 53
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Paper_model::getList(): Optional parameter $search declared before required parameter $perPage is implicitly treated as a required parameter
Filename: models/Paper_model.php
Line Number: 10
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 54
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property Paper_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
Line: 15
Function: _error_handler
File: /home/websi113/case/germark.com.tw/application/models/Paper_model.php
Line: 7
Function: __construct
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 54
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$Paper_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 54
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Product_model::getList(): Optional parameter $search declared before required parameter $perPage is implicitly treated as a required parameter
Filename: models/Product_model.php
Line Number: 10
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 55
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property Product_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
Line: 15
Function: _error_handler
File: /home/websi113/case/germark.com.tw/application/models/Product_model.php
Line: 7
Function: __construct
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 55
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$Product_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
Line: 55
Function: model
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 10
Function: __construct
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property ShareMenu_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
Line: 15
Function: _error_handler
File: /home/websi113/case/germark.com.tw/application/models/ShareMenu_model.php
Line: 7
Function: __construct
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 12
Function: model
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property News::$ShareMenu_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 12
Function: model
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$load is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
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Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$languages is deprecated
Filename: core/Loader.php
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Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$defaultLang is deprecated
Filename: core/Loader.php
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Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$perPage is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$benchmark is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$hooks is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$config is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$log is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$utf8 is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$uri is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$exceptions is deprecated
Filename: core/Loader.php
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Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$router is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$output is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$security is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$input is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$lang is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$db is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$session is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$pagination is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$Website_model is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$News_model is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$Paper_model is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$Product_model is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
Severity: 8192
Message: Creation of dynamic property SelfLoader::$ShareMenu_model is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
Line: 69
Function: view
File: /home/websi113/case/germark.com.tw/germark.php
Line: 320
Function: require_once
2024-10-04 一般
腸道菌可以合成許多種類的結合型膽汁酸，統稱為微生物結合膽汁酸(microbially conjugated bile acids，MCBA)；其中腸道菌攜帶的膽鹽水解酶(bile acids hydrolase/transferase，BSH/T)是主要關鍵酵素，可將不同氨基酸結合至各類膽酸上，增加MCBA多樣性。
進一步研究發現，BSH/T酵素蛋白序列會影響氨基酸的偏好，使得腸道菌也有不同的MCBA合成能力；由於MCBA也具備抗菌的效果，因此腸道菌組成除了會影響各種膽汁酸的種類與比例，也會間接再改變腸道菌相；各類氨基酸中，疏水性越高、其衍生的膽汁酸殺菌能力越強。
在小鼠實驗中，不同的MCBA在腸肝循環中會有不同程度的回收；人體在縮胃手術後，整體MCBA有減少，但沒有發現個別膽汁酸的顯著變化。
整體而言，腸道菌相影響膽汁酸組成、再影響腸道菌相，顯示出一種菌相自我調整的回饋迴路；若能調整膽汁酸組成，或許是調整菌相的另一種途徑。
發表於 Nature (IF 50.5)