Deprecated : Constant E_STRICT is deprecated in /home/websi113/case/germark.com.tw/system/core/Exceptions.php on line 75
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property CI_URI::$config is deprecated
Filename: core/URI.php
Line Number: 101
Backtrace:
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property CI_Router::$uri is deprecated
Filename: core/Router.php
Line Number: 127
Backtrace:
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$benchmark is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$hooks is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$config is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$log is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$utf8 is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$uri is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$exceptions is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$router is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$output is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$security is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$input is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$lang is deprecated
Filename: core/Controller.php
Line Number: 82
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$db is deprecated
Filename: core/Loader.php
Line Number: 396
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property CI_DB_mysqli_driver::$failover is deprecated
Filename: database/DB_driver.php
Line Number: 371
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Return type of CI_Session_files_driver::open($save_path, $name) should either be compatible with SessionHandlerInterface::open(string $path, string $name): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 132
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Return type of CI_Session_files_driver::close() should either be compatible with SessionHandlerInterface::close(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 294
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Return type of CI_Session_files_driver::read($session_id) should either be compatible with SessionHandlerInterface::read(string $id): string|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 168
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Return type of CI_Session_files_driver::write($session_id, $session_data) should either be compatible with SessionHandlerInterface::write(string $id, string $data): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 237
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Return type of CI_Session_files_driver::destroy($session_id) should either be compatible with SessionHandlerInterface::destroy(string $id): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 317
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Return type of CI_Session_files_driver::gc($maxlifetime) should either be compatible with SessionHandlerInterface::gc(int $max_lifetime): int|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 282
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: session_set_cookie_params(): Session cookie parameters cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 289
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 304
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 314
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 315
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 316
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 317
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 375
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: session_set_save_handler(): Session save handler cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 110
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: Warning
Message: session_start(): Session cannot be started after headers have already been sent
Filename: Session/Session.php
Line Number: 143
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$session is deprecated
Filename: core/Loader.php
Line Number: 1283
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$pagination is deprecated
Filename: core/Loader.php
Line Number: 1283
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property Website_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
File: /home/websi113/case/germark.com.tw/application/models/Website_model.php
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$Website_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: News_model::getList(): Optional parameter $search declared before required parameter $perPage is implicitly treated as a required parameter
Filename: models/News_model.php
Line Number: 10
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
File: /home/websi113/case/germark.com.tw/application/models/News_model.php
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$News_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Paper_model::getList(): Optional parameter $search declared before required parameter $perPage is implicitly treated as a required parameter
Filename: models/Paper_model.php
Line Number: 10
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property Paper_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
File: /home/websi113/case/germark.com.tw/application/models/Paper_model.php
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$Paper_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Product_model::getList(): Optional parameter $search declared before required parameter $perPage is implicitly treated as a required parameter
Filename: models/Product_model.php
Line Number: 10
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property Product_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
File: /home/websi113/case/germark.com.tw/application/models/Product_model.php
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$Product_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfController.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property ShareMenu_model::$currentLang is deprecated
Filename: core/SelfModel.php
Line Number: 15
Backtrace:
File: /home/websi113/case/germark.com.tw/application/core/SelfModel.php
File: /home/websi113/case/germark.com.tw/application/models/ShareMenu_model.php
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property News::$ShareMenu_model is deprecated
Filename: core/Loader.php
Line Number: 358
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$load is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$languages is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$defaultLang is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$perPage is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$benchmark is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$hooks is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$config is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$log is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$utf8 is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$uri is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$exceptions is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$router is deprecated
Filename: core/Loader.php
Line Number: 931
Backtrace:
File: /home/websi113/case/germark.com.tw/application/controllers/News.php
File: /home/websi113/case/germark.com.tw/germark.php
A PHP Error was encountered
Severity: 8192
Message: Creation of dynamic property SelfLoader::$output is deprecated
Filename: core/Loader.php
Line Number: 931
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一點抗生素，至少一年抗藥性 - Germark Biotechnology 微菌方舟生物科技
一點抗生素，至少一年抗藥性
【💬 背景介紹】
✅ 抗生素抗藥性 (antimicrobial resistance；AMR) 是全球性的公共衛生危機。
✅ 傳統的體外與動物模型難以真實模擬抗藥性在人體腸道菌群中的演化過程。
✅ 了解短期抗生素使用如何在人體內促進抗藥性演化，對於優化抗生素管理策略至關重要。
【💬 研究目標】
📢 在真實人類體內，直接觀察抗生素使用對腸道菌基因體演化的影響。
【💬 研究材料方法】
🧭 60 名健康成人接受短期抗生素環丙沙星 (ciprofloxacin) 治療。
🧭 於試驗期間收集縱向糞便樣本進行分析。
🧭 使用新開發的計算方法，PolyPanner，來分析 5,665 個細菌基因體。
🧭 識別出 230 萬個變異位點 (variants)。
【👨 實驗結果】
💪 腸道菌的抗藥性基因出現了選擇性掃掠 (selective sweeping)，代表特定基因變異迅速在腸道菌中擴散。
💪 抗藥性演化集中於 DNA 旋轉酶 (DNA gyrase)，特定位點變異造成氨基酸替換、驅動抗藥性。
💪 約 10% 易感腸道菌在細胞內自然 (de novo) 演化出抗藥性突變，並在抗生素停用後仍持續存在 10 週以上，模型推估至少一年內不會回到敏感狀態。
💪 這些抗藥性基因突變對細菌生長未造成明顯適應成本 (fitness costs)。
【💡 啟示】
👨🏻🔬 即使是短期抗生素使用，也能在人體內促進抗藥性突變的出現，並長期存在於腸道菌群中。
👨🏻🔬 抗生素使用策略應盡量精簡與謹慎，以避免不必要的抗藥性基因累積與傳播。
發表於 Nature (IF 50.5)
原文 https://www.nature.com/articles/s41586-025-08781-x